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A Buffalo chicken sub with a beer next to it and blue cheese crumbles around it.

Buffalo Chicken Sub

Meet the perfect party sandwich no one can resist — the Buffalo chicken sub! This spicy chicken sandwich takes less than 30 minutes to prepare and features shredded Buffalo chicken, gooey mozzarella, a drizzle of ranch dressing and tangy blue cheese crumbles, all on a toasted, buttery bun. You won’t find a more crowd-pleasing sandwich that’s perfect for casual gatherings and game day.
Course Burgers and Sandwiches
Cuisine American
Prep Time 10 minutes
Cook Time 15 minutes
Total Time 25 minutes
Servings 4 sandwiches
Calories 346kcal


  • Baking pan
  • Foil


  • 1 cup Frank's RedHot Sauce
  • 6 tablespoons butter divided
  • 2 cups shredded chicken
  • 1 cup shredded mozzarella preferably freshly grated
  • 4 hoagie rolls or French rolls split in the middle
  • Blue cheese crumbles for topping
  • Ranch dressing for topping


  • Turn the oven to 375 degrees. Heat the Frank's RedHot Sauce and 4 tablespoons butter together, reserving 2 tablespoons butter. Stir together to make one cohesive Buffalo sauce.
  • Toss together the Buffalo sauce and chicken until well coated.
  • Divide the chicken evenly to fill the hoagie or split French rolls and top with mozzarella. If your roll is completely split into two, top with the other half of the bread and place the subs in a baking pan. Cover the baking pan with foil.
  • Bake until the subs are heated through and the cheese melts, about 15 minutes. Remove the foil and bake for another three minutes to toast the bread.
  • As the subs bake, heat the remaining 2 tablespoons butter. When the subs finish baking, brush the bread with the melted butter. Enjoy!



  • Keep in mind, the ingredient totals are a guide. It really comes down to how large your hoagie rolls are. A smaller hoagie roll won't need as much filling while a big roll will need more. I based this recipe on large hoagie rolls from the grocery store bakery.
  • For the shredded chicken, a store-bought rotisserie chicken works perfectly.
  • Don't like blue cheese? Feel free to leave it out! I love it, but I know it's not everyone's favorite. You could also substitute it with goat cheese or feta for a cheesy crumble if you prefer those.
  • Nutritional information is only an estimate. The accuracy of the nutritional information for any recipe on this site is not guaranteed.


Serving: 1sub | Calories: 346kcal | Carbohydrates: 34g | Protein: 27g | Fat: 11g | Saturated Fat: 4g | Polyunsaturated Fat: 1g | Monounsaturated Fat: 3g | Cholesterol: 66mg | Sodium: 456mg | Potassium: 201mg | Fiber: 1g | Sugar: 6g | Vitamin A: 160IU | Calcium: 111mg | Iron: 12mg